ADVANCED NEUROCARE (ANC)
Welcome
Advanced NeuroCare (ANC) is a neurology practice located in Morristown, New Jersey, offering diverse treatment options for many neurological and psychiatric conditions. Dr. Jonathan Fellus MD specializes in Neuro-rehabilitation of acquired brain injury, especially Traumatic Brain Injury, birth injuries, and anoxic-ischemic brain injury; neuro-degenerative diseases such as dementia are also frequently assessed and managed.
The ANC team addresses both short and long-term disease consequences with a spectrum of therapies. A diagnostic functional Neuro-imaging leader, and Neurofeedback Therapy expert, Dr. Jonathan Fellus and his team offer this cutting-edge, non-invasive neuromodulation technique to promote neuroplasticity and healing. The goal is functional restoration of abnormal brain networks or circuitry.
Together with Dr James Halper, MD, we specialize in TBI, PTSD, Anxiety and Depression, Autism, Epilepsy, Sleep Disorders, Stroke, Headaches, Nerve and Muscle Disorders, Dementia, Tinnitus, post-Covid19 encephalopathy (anxiety, depression, brain fog, insomnia, fatigue etc.); Neuropsychiatric disease, and other neurological problems.
Furthermore, we are open to novel, experimental, and alternative approaches to diagnose and treat neurological or psychiatric diseases. Our philosophy is to combine complementary, alternative or holistic therapies to achieve the maximum relief from symptoms, optimizing brain function to the greatest level possible. With certain chronic or degenerative disorders, just maintaining a certain level of functioning can represent a clinical victory.
Finally, our commitment to excellence goes beyond daily clinical practice. When opportunities arise, we conduct and participate in research projects in pursuit of new scientific advances that may discover safer and more effective treatment options.
~ Jonathan Fellus, MD
DR. JONATHAN FELLUS
Neurologist
After years of hard work and strenuous studying, I began practicing as a professional Neurologist in 2000. My extensive medical knowledge, combined with an ongoing curiosity to learn about the latest trends, define my success in the medical field. To learn more about my medical and academic background, please read below.
WORK EXPERIENCE
Founder & CMO - Advanced NeuroCare, LLC Morristown & Flanders, NJ Dec. 2012 - July 2014; Feb. 2019-current
Fee-for-service clinical practice specializing in neuropsychopharmacological management of complex cognitive, emotional and behavioral sequelae of acquired brain injury. Also experienced in dementias, movement disorders, seizure disorders, headache, spasticity; and non-invasive, multimodal neuromodulation, QEEG, Neurofeedback
Technician & Admin Assistant - CIIT Medical Center and Dr.James Halper MD Plainview, NY July 2014 - Jan 2019 (CIIT Feb. 2016 - June 2018)
TMS and Neurodiagnostic/Neurotherapeutic Technician (CES, DCS, QEEG,
Neurofeedback) Administrative assistant and scribe to Neuropsychiatrist
Research/writing/literature search and material/copywriting for CIIT, a clinic in
Plainview Long Island. Clinical support duties.
Research Fellow - Center for Neurologic Study La Jolla, CA Jan.- May 2016 Founder/Director: Richard Smith, MD
Collaboration to prepare a major research manuscript for publication. Participated in a think-tank-style series of discussions to refine, expand, and stratify the scope of the syndrome of pseudobulbar affect (PBA).
Designed research studies to test Nuedexta’s efficacy in treating other neurologic conditions.
Co-Founder & Chief Medical Officer -Zahra, Moroccan Charity Salt Lake City, UT
Coordinating the creation of the Moulay Ali Institute for Rehabilitation in Marrakech, Morocco; Education, Training (of PT/OT staff), FundRaising; Liaison with all stakeholders; Built Neurorehabilitation Clinic treating 50 patients/day.
Scientific Adviser (2005-2011); Chief Medical Officer (2011—2014); Chief Research Coordinator (2014-2018) International Brain Research Foundation Flanders, NJ; Supervisor: Phil Defina, Ph.D.
Co-developed Neuromarker-driven, Neuromodulation Multimodal Clinical Care Protocol subsequently FDA-approved for DOD-funded retrospective & prospective research; Coordinated QEEG, Neurofeedback, electroceutical diagnostic/therapeutics
Director of Rehabilitation - Meadowlands Hosp. Medical Center Secaucus, NJ Feb.2011–Oct. 2012 Supervisor: Philip DeFina, Ph.D.
Ran 22 bed Rehab/Neurorehabilitation Unit
Increased census from 6 to 20
Developed Outpatient Neuromodulation Center with TMS, CES, Neurofeedback, QEEG, MEG capacity
Kessler Institute for Rehabilitation East/West Orange, NJ
Staff Neurologist (Aug. '97-Sept. ’98); Director of Brain Injury
Services (Sept. '98-Feb. 2011). 1997- 2011 Supervisor: Steve Kirshblum, MD
Oversaw program with the largest U.S. brain injury in-patient rehab unit capacity (88 beds) over 3 sites
Managed 14 in-patients
Developed Severe Disorders of Consciousness Program & other programs
Engaged in clinical research
Liaison with media
Trained PMR, Neurology, and Neurosurgery residents/medical students as well as rotating Geriatric and TBI Fellows
Managed new and follow-up outpatients
Co-directed Spasticity Clinic (Botox and Intrathecal Baclofen)
Co-PI Northern New Jersey Traumatic Brain Injury Model System, 2000-2004
RESEARCH EXPERIENCE
Director of Education and Training -2012-2018 Phil Defina, Ph.D. Chief
Scientific Officer - Phase 1/2, Single-Blind, Study of Safety and Efficacy of IBRF’s Advanced Care Protocol in Severe Disorders of Consciousness
Contributing Scientist & Researcher/Lecturer/Writer 2013, Randall Kaye, MD, Chief
Medical Officer, Avanir PRISM II: Safety Tolerability and Effectiveness
of NUEDEXTA in PBA patients with Dementia, Stroke and Traumatic Brain Injury;
Contributing Scientist, Researcher, Lecturer, Writer, Editor 2011 - 2012 Randall Kaye
,MD Chief Medical Officer, Avanir PRISM I: A Novel Research Tool
to Assess the Prevalence of PBA Symptoms in Different Neurological Conditions
Medical Monitor 2009—2010
Anna Barrett, MD Principal Investigator NIH/NINDS R01NS055808;
Building a science for treatment of post-stroke Spatial Neglect.
Site Principal Investigator - 2005 Jonathan Silver, MD 12-week Prospective, Double-Blind, Placebo-Controlled, Study Evaluating the Efficacy
and Safety of Exelon 3-6mg in Patients with TBI and Persistent Cognitive Deficits.
Site Clinical Researcher - 2005, Linnea Burmann Medtronic-Sponsored Multi-Center Trial of Intrathecal Baclofen for the Management
of Spasticity Associated with Stroke.
Research Scientist - 2004, Elie Elovic
Multi-Center, Open-Labeled Study of Safety of Repeated Doses of Botox-Purified Neurotoxin Complex for Treatment of Upper Limb Post-Stroke Spasticity
Principal Investigator - 2003
Randomized, Double-Blind, Placebo-Controlled Study of C105 (Levoamphetamine)
to Improve Memory in Anterior Communicating Artery Syndrome
EDUCATION & MEDICAL TRAINING
Kernan Rehabilitation Hospital; Neurorehabilitation Fellowship; Baltimore, MD July 1996-June 1997 Supervisor: Michael Makley, MD
Pennsylvania Hospital Neurology Residency; Philadelphia, PA July 1993-June 1996 Chairman: Thomas “Mac” Bosley, MD
Mountainside Hospital Internal Medicine; Montclair, NJ July 1992-June 1993 Residency Coordinator: Alan Matook, MD
Robert W. Johnson Medical School; Piscataway, NJ M.D., Aug. 1988-May 1992 Robert Wood Johnson Summer Research Scholarship, Student Rep., Graduation Speaker.
Rutgers College; New Brunswick, NJ BA (Neurobiology, Cum Laude) Sept. 1984-May 1988 Henry Rutgers Honors Program & Merit Scholarship, Phi Beta Kappa
POSTDOCTORAL TRAINING:
Mountainside Hospital Internal Medicine July 1992-June 1993 Residency Coordinator: Alan Matook, MD
Pennsylvania Hospital Neurology Residency July1993-June 1996 Chairman: Thomas “Mac” Bosley, MD Kernan
Rehabilitation Hospital Neurorehabilitation Fellowship July 1996-June 1997 Supervisor: Michael Makley, MD
LICENSURE:
New Jersey #MA66164 – Expires June 30,
CERTIFICATIONS:
Neurology Board Certified, April 1998 Recertified, March 2009
Narcotics NJ-CDS-D072654
NJ-DEA-BF4747854
UNIVERSITY APPOINTMENTS:
Clinical Assistant Professor of Neurology, UMDNJ-NJMS
Department of Neurosciences, May 1998-February 2011
HOSPITAL APPOINTMENTS:
Meadowlands Hospital Medical Center, Director of Rehabilitation
February 2011–October 2012
Kessler Institute for Rehabilitation, Staff Neurologist
August 1997–1998; Kessler Institute for Rehabilitation, Director
Brain Injury Services September 1998–February 2011
AWARDS/HONORS:
Daniel P Bohan Memorial Award
Clinician of the Year, 2011
Sean Reilly
TBI Fund Award, 2010
Inside Jersey Magazine
Best Doctors NJ (Neurology), 2009
Humanitarian Award
Paterson Federation Knights of Columbus, 2009.
Listed among “Best Doctors NY Metro Area”
New York Magazine, 2008-2011
Listed among “Best Doctors in America”
Castle Connelly, 2007-2009
Listed among “Best Doctors” for Neurology
New Jersey Monthly Magazine, 2004
Chief Resident in Neurology
Pennsylvania Hospital, 1995-1996
Medical School Graduation
Student Representative Speaker, 1992
Robert Wood Johnson Research Scholarship, 1990
Phi Beta Kappa, 1988, Graduated Cum Laude Rutgers College, 1988
Henry Rutgers Merit Scholarship, 1984-1988
Dean’s List
Rutgers College, 1984-1988
BOARD OF DIRECTORS:
Board of Directors, Brain Injury Association of New Jersey
2004-2006
Advisory Board, Epilepsy Foundation of New Jersey
2000- Present
Executive Board, American Society of Neurorehabilitation
May 2001-Present
Chairman Fellowship Committee, American Society of Neurorehabilitation September 2002-present
COMMITTEE ASSIGNMENTS:
Associate Project Director of Northern New Jersey Traumatic Brain Injury Model System, Effective September 2000.
Co-Chairman of Traumatic Brain Injury Team Committee, Kessler Institute for Rehabilitation September 2002-2011.
Executive Board, American Society of Neurorehabilitation
May 2001-2011
MEMBERSHIPS IN PROFESSIONAL SOCIETIES:
American Academy of Neurology, 1993-Present
American Society of Neurorehabilitation, 1995-Present
Brain Injury Association of New Jersey, 2004-Present
RESEARCH INTERESTS:
Pharmacological Treatment of Pseudobulbar effect and Neuropsychiatric Behaviors associated with Acquired Brain Injury
Neurorehabilitation after Traumatic Brain Injury
Evaluation and Treatment of Severe Disorders of Consciousness
EDITORIAL BOARDS:
Guest Reviewer, Journal of Head Trauma Rehabilitation
2003-2004
Editorial Board, Neuropsychiatry of Traumatic Brain Injury
2004
GRANT HISTORY:
Co-PI of a Phase1/2, Single-Blind, O1pen-Label Study to Evaluate the Safety and Efficacy of the International Brain Research Foundation (IBRF) Disorders of Consciousness Advanced Care/MultiCare Intervention Protocol (ACP/MCP) in Patients with Severe Disorders of Consciousness (2011).
Medical Monitor, NIH/NINDS R01NS055808
Building a science for treatment of post-stroke spatial neglect
2009-2010, PI Anna Barrett
Advanced Brain Imaging in Traumatic Brain Injury, Number: 09.0001.BIR 2009
A 12-week Prospective, Double-Blind, Placebo-Controlled, Multi-Center Study Evaluating the Efficacy and Safety of Exelon 3-6mg in Patients with TBI and Persistent Cognitive Deficits, 2005
Medtronic-Sponsored Multi-Center Trial of Intrathecal Baclofen for the
Management of Spasticity Associated with Stroke, 2005
Multi-Center, Open-Labeled Study of Safety of Repeated Doses of Botox-Purified Neurotoxin Complex for Treatment of Upper Limb Post-Stroke Spasticity, 2004
Principal Investigator. Randomized, Double-Blind, Placebo-Controlled Study of C105 (Levoamphetamine) to Improve Memory in Patients Suffering from Anterior Communicating Artery Syndrome, 2003
LECTURES:
Brain Injury Association of New Jersey
At the neuropharmacological crossroads for cognitive, behavioral, and psychiatric treatment for brain injury. May 2011
Bryn Mawr Rehab TBI Conference
Functional Neuromarkers and Neuroplasticity After Brain Injury: An Integrated Multimodal Rehabilitation Approach to Assessment and Treatment, March 2011
Burke Rehabilitation Hospital
Functional Neuromarkers and Neuroplasticity After Brain Injury: An Integrated Multimodal Rehabilitation Approach to Assessment and Treatment. December 2010
California Brain Injury Conference
Functional Neuromarkers and Neuroplasticity After Brain Injury: An Integrated Multimodal Rehabilitation Approach to Assessment and Treatment. November 2010.
Hadassah Hospital. Severe Disorder of Consciousness. August 2010
Beit Lowenstein Rehabilitation Hospital. Severe Disorder of Consciousness
Hershey Rehabilitation
Functional Neuromarkers and Neuroplasticity after Brain Injury: An Integrated Multimodal Rehabilitation Approach to Assessment and Treatment. June 2010
International Brain Injury Association
Functional Neuromarkers and Neuroplasticity after Brain Injury: An Integrated Multimodal Rehabilitation Approach to Assessment and Treatment. March 2010
Avanir Pharmaceuticals, Member Speakers' Bureau. January 2010-Present
Forest Labs, Speakers' Bureau. Pharmacology of Dementia. 2004-2009
Hackensack University Medical Center, Division of Geriatrics. Supervisor/Clinical Instructor. 2004–2010
Kessler Institute for Rehabilitation. Spasticity Management Following Acquired Brain Injury. February 2008
New Jersey Neurological Society
Pharmacologic Management of Cognitive, Behavioral and Psychological/Psychiatric Dysfunction Following Acquired Brain Injury
March 2008
AAN Chicago. Ten Sequelae of TBI That You Can and Should Address. April 2008
VA Communication. Diagnosis, Prognosis, and Treatment of Cognitive and Behavioral Sequelae of TBI. December 2007
American Medical Rehabilitation Providers Association Conference. Severe Disorders of Consciousness and the Advanced Treatment Protocol. October 2007
Hackensack University Medical Center, Division of Geriatrics. Supervisor, Clinical Instructor. 2006-2010
Brain Injury Association of New Jersey, 22nd Annual Seminar Psychostimulant Medication to Improve Cognitive Recovery After TBI. 2004
Allergan Speaker's Bureau, Spasticity Management for Therapists. 2003
Predoctoral Psychology Internship Didactic Series. Neuropsychiatric Disorders and Management. 2003
American Academy of Neurology Annual Conference Fatigue Post-Acquired Brain Injury. April 2003.
Westchester Medical Center Outcomes of Traumatic Brain Injury from the Prospective of Rehabilitation. September 2002.
Westchester Medical Center, Trauma Grand Rounds. Pharmacologic Management of Post-traumatic Neuropsychiatric and Neurobehavioral Syndromes. June 2002.
American Academy of Neurology, Annual Meeting. Management of post-TBI Neurobehavioral Syndromes-from Abulia to Agitation. May 2000 & May 2001.
Hackensack University Medical Center, TBI Conference. Pharmacologic Management of Post-traumatic Neuropsychiatric and Neurobehavioral Syndromes. March 2001
Fairleigh Dickinson University Preceptor for Psychopharmacology Practicum. 2001–2004
Lehigh Valley Medical Center, Trauma Grand Rounds Pharmacologic Management of Post-traumatic Neuropsychiatric/Neurobehavioral Syndromes. October 2000
Medtronic Speaker's Bureau Intrathecal Baclofen Management of Spasticity. 2000–present
St. Josephs Hospital Trauma Department, Grand Rounds Speaker Cognitive and Behavioral Management of Traumatic Brain Injury. January 2000
St. Barnabas Neurology Department, Grand Rounds Speaker Cognitive and Behavioral Management of Traumatic Brain Injury.October 1999
New Jersey Institute for Continuing Legal Education Traumatic Brain Injury Rehabilitation. September 1999
Audiotape discussant Current Thinking in Treatment of Chronic Pain; Volume 1, No.1. 1999
UMDNJ-Newark, Department of Neurosurgery, Grand Rounds Speaker
Abulia-Clinical Spectrum and Pharmacologic Management. November 1998
Contemporary Approaches to Managing Pain-Focus of Myofascial Pain.
September-November 1998
Grand Rounds Speaker Anticonvulsants-Current Applications in Neurological Conditions. January June 1998
CLINICAL AND HOSPITAL RESPONSIBILITIES:
Meadowlands Hospital Medical Center
Medical Director of Rehabilitation
February 2011-October 2012
Kessler Institute for Rehabilitation, West Orange Campus
Attending Physician on Brain Injury Unit
1997-2011
Kessler Institute for Rehabilitation
Neurological Consultant
1997-2011
Lecturer for Resident Education Series
Headache, Spasticity, Pharmacological Management, Stroke, Anoxia, Movement Disorders
1999-2010
RESEARCH APPOINTMENTS:
Chief Medical Officer, International Brain Research Foundation. Jan. 2010-Present
POSTERS:
American Academy of Neurology - March 2013
Zakrzewski CM, DeFina PA, Fellus JLDextromethorphan/Quinidine markedly reduces pseudobulbar affect and impulsive shopping in individuals with traumatic brain injury.
International Stroke Conference -February 2013
Fellus JL, Crumpacker D, Kantor D, et al. PRISM Registry: A novel tool to assess the prevalence of pseudobulbar affect symptoms.
United States Psychiatric and Mental Health Congress -November 2012
Crumpacker D, Fellus JL, Kantor D, et al. PRISM: A novel research tool to estimate the prevalence of pseudobulbar affect symptoms.
Neuroscience Education Institute Global Psychopharmacology Congress -October 2012
Kantor D, Fellus JL, Kaye RE, et al. PRISM Registry: A novel research tool to estimate the
prevalence of pseudobulbar affect symptoms.
American Neurological Association-October 2012
Kantor D, Fellus JL, Kaye RE, et al.PRISM: A novel research tool to determine prevalence of pseudobulbar affect.
North American Brain Injury Society -September 2012
Zakrzewski CM, DeFina PA, Fellus JL Dystonia and spasticity after traumatic brain injury: Does treatment with intrathecal baclofen also improve comorbid paroxysmal autonomic instability?
PUBLICATIONS:
PRISM: A Novel Research Tool to Assess the Prevalence of Pseudobulbar Affect Symptoms… Brooks BR, Crumpacker D, Fellus J, Kantor D, Kaye RE. PLOS 1 Published 8/21/2013; Available at: (http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072232)
Dextromethorphan/Quinidine effectively manages impulsive shopping behaviors in individuals with traumatic brain injury. Fellus JL, Zakrzewski CM, DeFina PA. -Functional Neurology, Rehabilitation, and Ergonomics 2016 [Accepted for Publication]
Dextromethorphan/Quinidine alleviates pseudobulbar affect and rapidly eliminates suicidal ideation in individuals with acquired brain injury. Fellus JL, DeFina PA, Zakrzewski CM. -Functional Neurology, Rehabilitation, and Ergonomics Vol. 4; No. 4; 2014
Improving outcomes of severe disorders of consciousness. DeFina PA, Fellus J, Thompson JWG, et al. - Restorative Neurology & Neuroscience 2010; 28: 769-780
The New Neuroscience Frontier: Promoting Neuroplasticity and Brain Repair in Traumatic Brain Injury. DeFina PA., Fellus J, Polito MZ, et al. -Clinical Neuropsychology 2009; 23: 1391-1399
Post-Anoxic Facial Myoclonus Triggered by Speaking but Not Singing: A Case Report. Donlon MM, Fellus JL. -American Journal of Physical Medicine & Rehabilitation 2009; 1:110
Endocrine Abnormalities and Fatigue After Traumatic Brain Injury. Elovic E, Doppalapudi HS, Miller M, DeLuca J, Masel BE, Fellus JL, Urban RJ. -Journal of Head Trauma Rehabilitation 2006; 21: 426-427
An interesting case of a closed skull penetrating brain injury. McLean J, Fellus J. -American Journal of Physical Medicine & Rehabilitation, 2006;85:277
Case series of Kernohan-Woltman syndrome and discussion of false localizing signs: The importance of physical examination in the rehabilitation setting. McKenna C,Fellus J. -American Journal of Physical Medicine & Rehabilitation, 2006; 85:
Baclofen pump insertion and central fever regulation in traumatic brain injury: Case report. Heath KM, Fellus JL.-American Journal of Physical Medicine & Rehabilitation, 2006; 85: 255
The relationship between fatigue and endocrine abnormalities in people who have sustained traumatic brain injury. Doppalapudi HS, Miller M, Millis S, Fellus JL, Masel BE, Urban RJ, Dunn J, Elovic EP. - American Journal of Physical Medicine & Rehabilitation, 2005;84:227
Cerebral Blood Flow Measurements in the Newborn Dog. Koons AH, Wurtzel D, Metcalf JM, Fellus J, Vannucci R, Hiatt M, Hegyi T. - Neonatology 1993; 63: 120-128.
ORAL PRESENTATIONS:
American Congress for Rehabilitation Medicine/American Society for Neurorehabilitation Fellus JL, Zakrzewski CM Spectrum of disinhibition syndromes after traumatic brain injury: From pseudobulbar effect on impulsive shopping. October 2012
European Federation of Neurological Societies PRISM: A novel research tool to determine prevalence of pseudobulbar affect. September 2012
Consortium of Multiple Sclerosis Centers America's Committee for Treatment and Research in Multiple Sclerosis Kantor D, Kaye RE, Fellus JL PRISM: A novel research tool to determine prevalence of pseudobulbar affect. June 2012
MEDIA APPEARANCES (1999-2013):
Media Broadcast & Print appearances:
CBS - (Columbia Broadcasting System) https://cbs.com
ABC - (The American Broadcasting Company) https://abc.com
NPR - (National Public Radio) https://npr.org
Fox 5 - (WNYW Television Station NYC) https://fox5ny.com
NY Times (The New York Times Company) https://nytimes.com
Chicago Sun Times (Newspaper) https://chicago.suntimes.com
Channel 9 - https://channel9.msdn.com/
Channel 11 - (WPXI - TV, NYC) https://wpxi.com
Channel 12 ( News 12, TV, New Jersey) https://newjersey.news12.com/
MSNBC (News-based pay television) https://msnbc.com
ADDITIONAL SKILLS & LANGUAGES:
Baclofen Pump management
Botulinum toxin Injection
Proficient in Hebrew; basic French, Italian, Spanish
CERTIFICATIONS, LICENSES, PROFESSIONAL MEMBERSHIPS, & AFFILIATIONS:
American Academy of Neurology, 1993-current
American Society of Neurorehabilitation, 1995-2014
Brain Injury Association of New Jersey, 2004-current
Board Certified in Neurology (ABPN), April 1998; Recertified, March 2009; Planning to recertify 2021
Medical License, New Jersey, 25MA06616400 (exp. 6/30/21); CDS D07265400 current
DEA License FF8290316 (exp. 9/30/21)
RESEARCH INTERESTS:
Pharmacological Treatment of Pseudobulbar Affect
Disinhibition/impulsivity and other Neuropsychiatric Behaviors associated with Acquired Brain Injury
Neurorehabilitation after Traumatic Brain Injury
Evaluation and Treatment of Severe Disorders of Consciousness including Brain Death
Rational Polypharmacy
Nutraceutical therapy for neurocognitive/neurobehavioral sequelae of brain injury and promoting neuro recovery/neurorestorative (plasticity)
Post Neuro-Covid Syndrome diagnostic and therapeutic management
QEEG characterization and Neurofeedback treatment of Covid19 Encephalopathy
DR. JAMES HALPER
Psychiatrist, Internal Medicine
EDUCATION
1965 B.A. Columbia College
NY, NY
1971 M.D. College of Physicians & Surgeons
Columbia University
NY, NY
POST DOCTORAL TRAINING
1971 – 1972 Intern (medicine) Columbia Presbyterian Hospital
NY, NY
1972 – 1973 Resident (medicine) Stanford University Hospital
Palo Alto, California
1973 – 1975 Clinical Fellow National Institutes of Health (NIAMMD)
Bethesda, Maryland
1975 – 1977 Fellow (Immunology) Rockefeller University Hospital
NY, NY
1982 – 1985 Resident (Psychiatry) Cornell University Medical College
Payne Whitney Clinic
NY, NY
LICENSURES AND CERTIFICATION
1971 125903 – 1 New York State
1975 American Board of
Internal Medicine
1989 American Board of
Psychiatry & Neurology
ACADEMIC APPOINTMENTS
1978 – 1982 Assistant Professor College of Physicians and Surgeons
(Medicine) Columbia University
NY, NY
1982-1983 Adjunct Asst. Prof. Cornell University Medical College
of Medicine NY, NY
in Psychiatry
1985 – 1987 Instructor Cornell University Medical College
Dept of Psychiatry NY, NY
1987 – 1988 Assistant Professor Cornell University Medical College
Dept of Psychiatry NY, NY
1988 – 1989 Assistant Professor Mount Sinai Medical College
Dept of Psychiatry NY, NY
1988 – 1992 Assistant Professor Cornell University Medical College
Dept of Psychiatry NY, NY
1992 – 1994 Assistant Professor Cornell University Medical College
of Clinical Psychiatry NY, NY
1993 - Clinical Associate NYU Medical Center
Professor of Psychiatry NY, NY
1997 – 1999 Assistant Professor Weill Medical College (Cornell)
of Psychiatry NY, NY
HOSPITAL APPOINTMENTS
1975 – 1977 Assistant Physician Rockefeller University Hospital
NY, NY
1978 – 1982 Assistant Attending Columbia Presbyterian Hospital
Physician NY, NY
1982 – 1985 Assistant Psychiatrist New York Hospital
(PGY 2 – 4) NY, NY
1985 – 1988 Clinical Affiliate New York Hospital
NY, NY
1988 – 1989 Assistant Attending Mount Sinai Medical Center
Physician NY, NY
1989 – 1992 Director North Shore University
Psychopharmacology Manhasset, NY
1992 – 1997 Chief Lenox Hill Hospital
Psychiatry OPD NY, NY
1997 – 1999 Attending Psychiatrist New York, Hospital
Director, ECT Service NY, NY
Director, Psychotic Disorders Service
2000- Consulting Psychiatrist Lenox Hill Hospital
Associate Chief for NY, NY
Research
2005 – Present Consulting Psychiatrist Lenox Hill Hospital
Chief for Research NY, NY
AWARDS AND HONORS
1965 Magna cum Laude Columbia College
1965 – 1966 Woodrow Wilson Fellow Columbia University
Dept. of Chemistry
NY, NY
1966 – 1971 Life Insurance Medical College of Physicians and Surgeons
Research Award Columbia University
NY, NY
1985 Resident Research Award American Psychiatric Association
1985 William T. Lhamon Prize Payne Whitney Clinic
for Residents Research New York Hospital
1985 – 1988 First Reader’s Digest Payne Whitney Clinic
Research Fellowship New York Hospital
Psychiatry
MAJOR COMMITTEE ASSIGNMENTS
1989 – 1992 Institutional Review North Shore University Hospital
Board Manhasset, NY
1992 – 1997 Institutional Review Lenox Hill Hospital
Board NY, NY
1992 – 1994 Outpatient Department Lenox Hill Hospital
Committee NY, NY
1997-1998 ECT Committee New York-Presbyterian Hospital
2005- Institutional Review Board Lenox Hill Hospital N.Y. ,N.Y.
2005- Executive Committee Lenox Hill Hospital N.Y. ,N.Y.
MEMBERSHIPS, OFFICES, & COMMITTEE ASSIGNMENTS IN PROFESSIONAL SOCIETIES
1985- American Psychiatric Association
1990 - American Society for Clinical Psychopharmacology (ASCP)
Member ASCP Curriculum Committee
(Responsible for Typical and Atypical Antipsychotics Sections)
2000 EEG and Clinical Neurosciences Society
MAJOR RESEARCH INTERESTS
Psycho-immunology, Psycho- rheumatology, Schizophrenia
PRINCIPAL CLINICAL & HOSPITAL SERVICE RESPONSIBILITIES
1992 – 1997 Clinical responsibility for inpatients and outpatients on the Clozaril
Treatment Program
Clinical responsibility for outpatient treatment
Lenox Hill Hospital OPD
1997 – 1998 Director of ECT Program
Department of Psychiatry
New York Hospital
1997 – 1998 Director, Psychotic Disorders Services
New York Hospital
MAJOR ADMINISTRATIVE RESPONSIBILITIES
Administering Psychiatric Outpatient Division
1992-1997 Department of Psychiatry
Lenox Hill Hospital
1992-1997 Administering Clozaril Treatment Program
Department of Psychiatry
Lenox Hill Hospital
GRANTS
9-30-1993-9-29-11995 “Guided Imagery as a Treatment for Asthma”
NIH 1R21 RR0926-01
TEACHING EXPERIENCE
North Shore University Hospital
1982 – 1992 Co – Director, PGY II
Psychopharmacology Course
1989 – 1992 Director, PGY III
Psychopharmacology Course
1989 – 1992 Co – Director, PGY IV
Advanced Psychobiology Seminar
Payne Whitney Clinic, New York Hospital
1989 – 1993 Co – Director
Advanced Psychobiology Seminar
1997 – 1998 Section Director, Psychotic Disorders
Director, ECT
Lenox Hill Hospital
1993 – 1995 Director, PGY II
Psychopharmacology Teaching Conference
1993 – 1997 Director, PGY IV Psychopharmacology Seminar
1997 - Guest Lecturer
NYU Medical Center
1994 – 1997 Advanced Psychopharmacology (PGY IV)
1995 – 1997 Introduction to Neurobiology (PGY II)
1994 - Present Advanced Psychopharmacology (PGYIV)
Individual Supervision of residents in all institutions
SELECTED PUBLICATIONS
Halper, J.P., Latoviski, N., Bernstein, H. and Beychok, S. Optical Activity of human lysozyme. Proc. Nat. Acad. Sci. 68:517-522,1971.
Halper, J.P., and Metzger, H. The interaction of IgE with rat basophilic leukemic cells. VI. Inhibition by IgGa immune complexes. Immunochem. 13: 907 – 913, 1976.
Vande Stouwe, R.A., Kunkel, H.G. Halper, J.P.,. and Wekslar, M.E. Autologous mixed lymphocyte culture reaction and generation of cytotoxic T cells. J. Exp. Med. 146:1809 – 1814, 1977.
Winchester, R.J., Ross, G.D., Jarowski, C.I., Wang, C.Y., Halper, J.P., and Broxmeyer, H.E. Expression of Ia – like molecules of human granulocytes during early phases of differentiation. Proc. Nat. Acad.Sci. 74: 4012 – 4021, 1977.
Halper, J.P., Fu, S.M., Wang, C.Y., Winchester, R., and Kunkel, H.G. Patterns of expression of human “Ia – Like” antigens during the terminal stages of B cell development. J Immunol. 120: 1480 – 1485, 1978.
Fu, S.M., Chiroazzi, N. Kunkel, H.G. Halper, J.P., and Harris, S. Induction of in vitro differentiation of leukemic B lymphocytes. J. Exp.Med. 148: 1570 – 1578, 1978.
Halper, J.P.,.Fu, S.M. Winchester, R.J. and Kunkel H.G. Poor mixed lymphocyte reaction capacity of leukemic B lymphocytes of chronic lymphocytic leukemia patients despite the presence of Ia antigens. J Clin. Invest. 64: 1141 – 1148, 1979.
Knowles, D.M., Halper, J.P., Machin, G., and Sherman, W.H. Acid alphanaphyl esterase activity in human neoplastic lymphoid cell; Usefulness as a T cell marker. Am. J. Pathol. 96: 257 – 272, 1979.
Knowles, D.M., Jakobiec, F.A. and Halper, J.P. Immunologic characterization of ocular and adnexal lymphoid tumors. Am. J. Ophthalmol. 87: 603 – 619, 1979.
Gottlieb, A.B., Fu, S.M., Yu, D.T.Y., Wang, C.Y., Halper, J.P., and Kunkel, H.G. The nature of human allogenic and autologus MLC reactions: Role of Isolated IgM – bearing B cells. J. Immunol. 123: 1498 – 1503, 1979.
Halper, J.P., Knowles, D.M., and Wang, C.Y. Ia antigen expression by human malignant lymphomas: correlation with conventional lymphoid markers. Blood 55: 373 – 382, 1980.
Knowles, D.M. and Halper, J.P. Human medullary and cortical thymocytes are distinguishable according to the presence or absence of cytochemically demonstrable acid naphythyl acetate esterase (ANAE) activity. J. Immunol. 125: 2823 – 2826, 1980.
Machin, G.A., Halper, J.P., and Knowles, D.M. Cytochemically demonstrable – B – glucuronidase activity in normal neoplastic human lymphoid cells. Blood 56: 1111 – 1119, 1980.
Friedman, S.M., Thompson, G., Halper, J.P., and Knowles, D.K. OT CLL: A human T cell chronic lymphocytic leukemia that produces IL – 2 in high titer. J. Immunology 128: 935 – 940, 1982.
Roth, P. Halper, J.P., Pernis B., and Weinstein, I.B. Effect of phorbol esters on expressions of Ia antigens and surface immunoglobulins of 23 cases. Am.J.Pathol. 106: 187 – 203, 1982.
Halper, J.P., Kabat, E.V., Osserman, E.F., Tonda, P. and Pernis, B. Spontaneous in vitro differentiation of antigen specific lymphocytes from a patient with IgM gammopathy. J.Clin. Invest. 70: 1292 – 1299, 1982.
Halper, J.P., Tolidjian, B., and Knowles, D.M. Acid – napthyl acetate esterase in human B – cell differentiation. Cell Immunol. 72: 36– 374, 1982.
Siris, E.S. Grossbard, L., Halper, J.P., Blume, R.S. and Jacobs, T.P. Chronic Lymphocytic leukemia and hypercalcmia: Treatment with dichloromethylene. Metab. Bone. and Rel. Res. 5: 61 – 63, 1983.
Knowles, D.M., Halper, J.P., Azzo, W., Wang C.Y. Reactivity of monoclonal antibodies. Leu1 and OKT 1 with malignant human lymphoid cells. Cancer 52: 1369 – 1377, 1983.
Halper, J.P., Mann, J.J., Weksler, J.J. Bilezikian, J.P., Sweeney, J.A., Brown, P.P. and Golbourne, T. Beta adrenergic receptors and cyclic AMP levels in intact human lymphocytes: Effects of age and gender. Life Sciences 35: 855 – 863, 1984.
Mann, J.J., Brown, R.P., Halper, J.P., Sweeney, J.A., Kocsis, J.H., Stokes, P.E. and Bilezikian, J.P. Reduced lymphocyte beta receptor sensitivity in patients with endogenous depression and psychomotor agitation. N Engl.J.Med. 313:715 – 720, 1985.
Halper, J.P., Brown, R.P., Sweeney, J.A., Kocsis, J.H., Peters, A, and Mann, J.J. Blunted beta – adrenergic responsivity of peripheral blood mononuclear cells in patients with endogenous depression: Isoproterenol dose responsive studies. Arch Gen. Psychiatry 45: 241 – 244, 1988.
Mann, J.J., Mahler, J.C., Wilner, P.J., Brown, R.P., Johnson, K.S., Kocsis, J.H., Chen, J. Normalization of blunted lymphocyte beta adrenergic responsivity in melancholic inpatients by course of electroconvulsive therapy. Arch Gen. Psych. 47: 461 – 464, 1990.
Halper, J.P., Miller, A. , Trestmar, R., Santucci, A., Lackner, C., and Stein, M. Biochemical mechanisms of stress induced impairment of rat T cell mitogenesis. J Neuroimmunol. 32: 242 – 247, 1991.
McBride, P.A., DeMeo, M.D., Sweeney, J.A. Halper, J.P., Mann, J.J., Shear, M.K. Neuroendocrine and behavioral responses to challenge with the indirect serotonin agonist dl – fenfluramine in adults with obsessive – compulsive disorder. Biol. Psychiatry 32: 19 – 34, 1992.
Sweeney, J.A, Palumbo, D., Halper, J.P., Shear, M.H. Abnormal eye pursuit movements in obsessive – compulsive disorder. Psychiatry Res. 42: 1 – 11, 1992.
Mann, J.J., Halper, J.P., Wilner, P.J., Sweeney, J.A., Mieczkowski, T.A., Chen, J. Stokes, P.E., and Brown, R.P. Subsensitivity of adenylyl cyclases – coupled receptors on mononuclear leukocytes from drug – free inpatients with a major depressive episode. Biol. Psychiatry 42: 859 – 870, 1997.
Epstein, G., Barrett, E.A.M., Halper, J., Seriff, N.S., Phillips, K. & Lowenstein, S. (1997). Alleviating asthma with mental imagery: A phenomenological approach. Alternative and Complementary Therapies, 3, 42-52.
Halper, J.P, Epstein, G. N., ,. Barrett, E.A M., Birdsall, C., McGhee, M., Phillips, K., and Lowenstein, S. A study of mind-body changes in adults with asthma who practice mental imagery. Alternative Therapies in Health and Medicine, 10:4, 2004.
John E.R., Prichep L.S., Winterer G., Herrmann W.M., diMichele F., Halper J., Bolwig T.G. and Cancro R. Electrophysiological subtypes of psychotic states. Acta Psychiatrica Scandinavica. 116:17-35, 2007
John, E.R., Halper, J.P., Lowe, R.S., Merkin, H., DeFina P. and Prichep, L.S. Source Imaging of QEEG as a method to detect awareness in a person in vegetative state. Brain Injury 25:426-432, 2011
PUBLICATIONS IN PREPARATION OR SUBMITTED
John, E.R. Halper J.P. Lowe, R.S., Isenhart, R., de Fina, P. Schwartz, D. , Fellus, J., Merkin, H, Howard, B., Kiernan, T. Prichep, L.P QEEG Guided Restoration of mental functions of patients in vegetative states. A new approach to assessment and management of patients in depressed states of consciousness
BOOK CHAPTERS AND REVIEWS
Halper, J.P. and Mann, J.J. Cardiac effects of antidepressant medications. Br. J. Psychiatry. 153 (Suppl. 3): 87-98, 1988.
Mann, J.J., Halper, J.P., Sweeny, J.A., DeMeo, M., Peters, A, Wilner, P.J., Kocsis, J.H., and Brown, R.P. Mechanism of altered beta-adrenergic responsivity in depressive disorders. R.H. Belmaker and M. Sandler (eds) “Progress in Catecholamine Research Part C,” Clinical Aspects 249-253. Alan R. Liss Inc., 1988.
Mann, J.J., Halper, J.P., Brown, R.P., McBride. A, Sweeney, J.A., Peters, A., Wilner, P.J. Peripheral blood cell biological markers in depression. In B. Lerer, S. Gershon (eds.) New Directions in Affective Disorders. Springer-Verlag, New York, 1989.
Halper, J.P., Brown, R.P., Sweeney, J.S., Kocsis, J.H., Peters, A., and Mann, J.J. Lymphocyte beta-adrenergic responsivity in depression: Implications for immune function. In A. Miller (ed) Depressive Disorders and Immunity. American Psychiatric Press, Washington, D.C. 13-151, 1991.
Halper, J.P., Immunocyte receptors and second messengers in psychoneuroimmunology. In J. Gorman, R. Kertzner (eds.) Psychoimmunology Update. American Psychiatric Press, Washington, D.C. 113-1551, 1991.
Rubin, M and Halper, J.P. Reflex Sympathetic Dystrophy. In S. Paget, J. Beary, C. Christian, P. Pellicci (eds.), Manual of Rheumatology and Outpatient Orthopedics: Diagnosis and Therapy. Little Brown and Co., Boston. 297-401, 1993.
Halper, J.P. and Rubin, M. Neurologic psychiatric neuropsychiatric manifestation of rheumatology disease. In S. Pager, J. Beary, C. Christian, P. Pellicci eds) Manual of Rheumatology and Outpatient Orthopedics: Diagnosis and Therapy. Little Brown and Co., Boston. 360-396. 1993.
Halper, J.P. Neuropsychiatric effects of corticosteroids. In A. Lin, S. Paget (eds.) Principles of Corticosteroid Therapy. Arnold Publishers, London, 2002.
SELECTED PRESENTATIONS
Neurophysiological Basis of Meditation at East/West Medical Conference, Beth Israel Hospital, May 1998.
Neurophysiology of Bliss States in Tibetan Meditation at First International Conference on Tibetan Medicine, Wash DC, November 1998
Grand Rounds/Case Conferences, Manhattan State Psychiatric Institute, 2004-2008
Grand Rounds Lenox Hill Hospital “Metabolic Syndrome” February 2008
Fibromyalgia: “Present Concepts and Future Directions” at American Psychiatric Association Annual Meetings 2004-2008